Sharp AL 1655CS AL-1655CS Operation Manual - Page 110

Chronic Effect, Waste from Residues, Contaminated Packaging, H.Muhle, B.Bellmann, O.Creutzenberg

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Chronic Effect MATERIAL SAFETY DATA SHEET Page : 4/4 Date Revised : Jul. 31, 2002 Date Issued : Jun. 1, 1998 MSDS No. F-30831 : In a study in rats of chronic inhalation exposure to a typical toner, a mild to moderate degree of lung fibrosis was observed in 92% of the rats in the high concentration (16mg/m3) exposure group, and a minimal to mild degree of fibrosis was noted in 22% of the animals in the middle (4mg/m3) exposure group, but no pulmonary change was reported in the lowest (1mg/m3) exposure group, the most relevant level to potential human exposures. 12.ECOLOGICAL INFORMATION No data are available. 13.DISPOSAL CONSIDERATIONS Waste from Residues : Waste material may be dumped or incinerated under conditions which meet all federal, state and local environmental regulations. Contaminated Packaging : Waste may be disposed or incinerated under conditions which meet all federal, state and local environmental regulations. 14.TRANSPORT INFORMATION UN Classification : None Not classified as hazardous for transport. 15.REGULATORY INFORMATION US Information TSCA(Toxic Substances Control Act) : All chemical substances in this product comply with all applicable rules or order under TSCA. SARA(Superfund Amendments and Reauthorization Act) Title III 302 Extreme Hazardous Substance : None 311/312 Hazard Classification : None EU Information 1999/45/EC and 67/548/EEC Symbol & Indication : Not required R-Phrase : Not required 76/769/EEC : All chemical substances in this product comply with all applicable rules or order under 76/769/EEC. 16.OTHER INFORMATION NFPA Rating (USA) : Health=1 Flammability=1 Reactivity=0 WHMIS Legislation (Canada) : This product is not a controlled product. References IARC(1996) : IARC monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 65, Printing Process And Printing Inks, Carbon Black and Some Nitro Compounds, Lyon, pp.149-261 H.Muhle, B.Bellmann, O.Creutzenberg, C.Dasenbrock, H.Ernst, R.Kilpper, J.C.MacKenzie, P.Morrow, U.Mohr, S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats. Fundamental and Applied Toxicology 17, pp.280-299. The information on this data sheet represents our current data and best opinion as to the proper use in handling of this product under normal conditions. However, all materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which exist. 108

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108
MATERIAL
SAFETY
DATA
SHEET
Page : 4/4
Date Revised : Jul. 31, 2002
Date Issued
: Jun.
1, 1998
MSDS No. F-30831
Chronic Effect
:
In a study in rats of chronic inhalation exposure to a typical toner, a mild to moderate degree of
lung fibrosis was observed in 92% of the rats in the high concentration (16mg/m
3
) exposure
group, and a minimal to mild degree of fibrosis was noted in 22% of the animals in the middle
(4mg/m
3
) exposure group, but no pulmonary change was reported in the lowest (1mg/m
3
)
exposure group, the most relevant level to potential human exposures.
12.ECOLOGICAL INFORMATION
No data are available.
13.DISPOSAL CONSIDERATIONS
Waste from Residues
:
Waste material may be dumped or incinerated under conditions
which meet all federal,
state and local environmental regulations.
Contaminated Packaging :
Waste may be disposed or incinerated under conditions which meet all federal, state
and local environmental regulations.
14.TRANSPORT INFORMATION
UN Classification
: None
Not classified as hazardous for transport.
15.REGULATORY INFORMATION
US Information
TSCA(Toxic Substances Control Act) :
All chemical substances in this product comply with all applicable rules or order under TSCA.
SARA(Superfund Amendments and Reauthorization Act) Title III
302 Extreme Hazardous Substance : None
311/312 Hazard Classification
: None
EU Information
1999/45/EC and 67/548/EEC
Symbol & Indication
: Not required
R-Phrase
: Not required
76/769/EEC
: All chemical substances in this product comply with all applicable rules or
order under 76/769/EEC.
16.OTHER INFORMATION
NFPA Rating (USA)
: Health=1
Flammability=1
Reactivity=0
WHMIS Legislation (Canada)
: This product is not a controlled product.
References
IARC(1996) : IARC monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 65,
Printing Process
And Printing Inks, Carbon Black and Some Nitro Compounds, Lyon, pp.149-261
H.Muhle, B.Bellmann, O.Creutzenberg, C.Dasenbrock, H.Ernst, R.Kilpper, J.C.MacKenzie, P.Morrow, U.Mohr,
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
The information on this data sheet represents our current data and best opinion as to the proper use in handling of this
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.